The sixth Global Environment Outlook (GEO-6) Assessment for the pan-European region paints a comprehensive picture of the environmental factors contributing to human health and well-being at the regional level. Backed by a large body of recent, credible scientific evidence, regional-wide consultations and a robust intergovernmental process, the assessment demonstrates that regional and global multilateral environmental agreements have improved environmental conditions in the pan-European region. It also highlights the complexity of the interlinked environmental, social and economic challenges now confronting decision makers.