Human activities have introduced significant amounts of anthropogenic chemicals into marine ecosystems,posing threats to aquatic biodiversity and human health. Although, traditional marine monitoring focus primarilyon legacy pollutants, the presence and potential risks associated with complex emerging chemical mixturesshould not be neglected. In the context of the present study organized via OSPAR Commission andsupported by NORMAN network, 52 marine samples were gathered from North-East Atlantic Ocean. State-of-theartHRMS-based analytical workflows were employed to identify their chemical fingerprint. 132 organic pollutantswere identified through wide-scope target screening of more than 2,400 environmentally relevant organicpollutants. The HRMS data were digitally stored in NORMAN DSFP and 134 additional chemicals were tentativelyidentified through suspect screening of more than 65,000 chemicals. The list included legacy pollutants,along with emerging pollutants, their metabolites and transformation products. A simplified environmental riskassessment was conducted, aiming to prioritize substances based on their potential risks to the marine ecosystem.This study provides a valuable snapshot of the marine pollution, offering insights into chemical occurrence andrisks. The findings can support marine scientists, environmental managers and policymakers in identifyingpollutant sources, understanding their impacts, and informing regulatory measures to mitigate threats to marineecosystems.